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AB - We demonstrate a highly sensitive label-free Mach-Zehnder interferometer biosensor based on silicon nitride slot waveguide. Unlike the conventional MZI sensors, the sensing arm of the sensor consists of a slot waveguide while the reference arm consists of a strip waveguide. The bulk refractive index sensitivity of the slot waveguide MZI sensor was found to be 1864π/RIU with 7 mm long slot waveguide sensing arm, which shows higher sensitivity compared to the conventional MZI device based on silicon nitride. The biosensing capability of the developed slot waveguide MZI was investigated using biotin-streptavidin binding as a model system. The sensitivity of the system was demonstrated down to 18.9 fM or 1 pg/ml of streptavidin solution and to the best of our knowledge, it is the best reported experimental value for the limit of detection of a MZI sensor.
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Logical replication brings over only the SQL-like changes. Logical replication data has to be decoded using a plugin. After replication slots came in with PostgreSQL 9.4, you don’t have to worry about wal_keep_segments because replication slots make sure that the WAL files are kept forever.
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